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Cancer-drug AM580: the Anti-viral drug?

Doctors from Hong Kong have found in animal experiments that a cancer drug is effective against flu, SARS, MERS, ZIKA, and many other viruses. The active ingredient, however, could also have strong side effects.

A Coronavirus. The cancer drug AM580 could dry out such virus such as SARS – in the cell of a quasi””

A Team led by microbiologist Yuen Kwok-Yung has announced that the cancer drug AM580, apparently, can fight viruses. The medic told the AFP news Agency that the active ingredient in the mice experiment as a “highly potent” ‘ve been proven and be able to break “the life cycle of various viruses”. The researchers have made their discovery on 10. January in the journal Nature Communications published.

Some viruses, such as SARS and MERS are highly contagious. Early containment is therefore very important.

Effective against a variety of virus types

Accordingly, AM580 acts both against the most common flu strains H1N1, H5N1 and H7N9, as well as against far more dangerous virus. This includes the severe acute respiratory syndrome (SARS) in the Middle East spread of MERS-corona virus, the mosquito borne ZIKA Virus, or the human Enterovirus 71, a causative agent of Hand-foot-mouth disease, also known as “false foot-and-mouth disease”.

Thus, the drug could be – if it will play in approved for once – an “important role in the early combat of epidemics,” said Yuen Kwok-yung.

Because viruses are very adaptable and quickly resistance can develop, try not doctors, to fight them directly, but to deprive you of your food.

For example, by being denied the viruses, certain fatty acids or lipids, which they need for reproduction. So, too, AM580 works.

More: bird flu – a never-ending story

Drug damages the cells

However, there is also a Problem: The lipids in the cells infected with the virus, and in which the propagation takes place. This, in turn, can lead to damage of the cell itself, and thus to further side effects.

After the treatment, you must regenerate the cells. “If not very carefully done, the risk of side effects is quite worrying,” warns the doctors.

In a next step, the researchers want to test the drug now in pigs and monkeys, before the first Tests can be carried out on human subjects. This is likely to come back for at least eight years.

More about viruses: Epstein-Barr Virus: the success of in search of vaccine


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